Cancer-focused Research | IIT Indore | Data-led Biomedical Design

Design & Develop Quercetin Nanoparticles for Theranostics

Data-driven research in nano-based cancer therapeutics and diagnostics

1. The Problem

Quercetin is a potent plant-based flavonoid with known anticancer, antioxidant, and anti-inflammatory effects. However, its clinical application is limited by:

• Poor water solubility
• Low bioavailability
• Rapid clearance from the body

Despite strong therapeutic potential, free quercetin is nearly ineffective without a delivery strategy.

1.1 The Objective

Design and develop a biocompatible, nanoparticle-based delivery system for Quercetin that:

2. My Role

I independently led the entire R&D lifecycle:

• Formulation strategy
• Experiment planning
• Iterative synthesis
• Characterization and testing
• Data interpretation and reporting

3. Experimental Strategy

4. Data Highlights

5. Key Figures to Include

Schematic of nanoparticle synthesis 

SEM Morphology

DLS data

Zeta Potential

UV-Vis + Fluorescence comparison

MTT assay results on HeLa & A549 cells

Fluorescence images of Qct-NP-treated cells

What I Learned

This project taught me how to:

• Translate theory into experimental design
• Handle complex scientific instrumentation and datasets
• Drive research with a focus on real-world biological application
• Synthesize qualitative and quantitative data into clear outcomes